Graft-Versus-Host Disease by C. Duncan | OPENPediatrics
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What is Graft Versus Host Disease? | Dana-Farber Cancer Institute
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Stephen J Ronan MD on X: "Perhaps a little caution is warranted. Cord cells are allogeneic, meaning they come from another person, not from you. Cord MSCs carry low HLA class II, so rejection and graft-versus-host disease are uncommon. The real risks with 70 million cells by IV are clotting from tissue factor, most cells getting trapped in the lungs, donor screening and infection, possible HLA sensitization, and no long-term data. The FDA has approved one MSC product so far, Ryoncil, in Dec 2024
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